Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Two-dimensional Gel Electrophoresis

Two-dimensional Gel Electrophoresis

Two-dimensional gel electrophoresis is a high-resolution protein separation method first introduced by O' Farrell and Klose in 1975. This method involves protein separation by two dimensions, mass and charge, making it more accurate than one-dimensional gel electrophoresis.
The first dimension separation uses the isoelectric focusing or IEF technique performed on immobilized pH gradient (IPG) strips that separate proteins according to their isoelectric points.
Biological samples, such as cells...

Motion Of A Charged Particle In A Magnetic Field

Motion Of A Charged Particle In A Magnetic Field

A charged particle experiences a force when moving through a magnetic field. Consider the field to be uniform and the charged particle to move perpendicular to it. If the field is in a vacuum, the magnetic field is the dominant factor determining the motion. Since the magnetic force is perpendicular to the direction of motion, a charged particle follows a curved path. The particle continues to follow this curved path until it forms a complete circle. Another way to look at this is that the...

Magnetic Field due to Moving Charges

Magnetic Field due to Moving Charges

A stationary charge creates and interacts with the electric field, while a moving charge creates a magnetic field.
Consider a point charge moving with a constant velocity. Like the electric field, the magnetic field at any point is directly proportional to the magnitude of the charge and inversely proportional to the square of the distance between the source point and the field point. However, unlike the electric field, the magnetic field is always perpendicular to the plane containing the line...

Electrophoresis: Overview

Electrophoresis: Overview

Electrophoresis is a powerful analytical separation technique that relies on the differential migration of charged species when subjected to an electric field. The core strength of electrophoresis lies in its ability to separate high-molecular-weight species in complex mixtures. It has found widespread use in biochemistry, molecular biology, and analytical chemistry, allowing the separation of compounds like amino acids, nucleotides, carbohydrates, and proteins with excellent resolution.
There...

Motional Emf

Motional Emf

Magnetic flux depends on three factors: the strength of the magnetic field, the area through which the field lines pass, and the field's orientation with respect to the surface area. If any of these quantities vary, a corresponding variation in magnetic flux occurs. If the area through which the magnetic field lines are passing changes, then the magnetic flux also changes. This change in the area can be of two types: the flux through the rectangular loop increases as it moves into the magnetic...

Magnetic Fields

Magnetic Fields

A moving charge or a current creates a magnetic field in the surrounding space, in addition to its electric field. The magnetic field exerts a force on any other moving charge or current that is present in the field. Like an electric field, the magnetic field is also a vector field. At any position, the direction of the magnetic field is defined as the direction in which the north pole of a compass needle points.
A magnetic field is defined by the force that a charged particle experiences...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Active many-particle systems and the emergent behavior of dense ant collectives.

Reports on progress in physics. Physical Society (Great Britain)·2024

Same author

Poly(N-isopropylacrylamide) microgel swelling behavior and suspension structure studied with small-angle neutron scattering.

Physical review. E·2023

Same author

Orientational Correlations in Active and Passive Nematic Defects.

Physical review letters·2021

Same author

Osmotic pressure of suspensions comprised of charged microgels.

Physical review. E·2021

Same author

Spontaneous deswelling of microgels controlled by counterion clouds.

Physical review. E·2019

Same author

Phase behavior of binary and polydisperse suspensions of compressible microgels controlled by selective particle deswelling.

Physical review. E·2018

Search research articles

Related Experiment Video

Updated: Jul 1, 2026

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Published on: February 13, 2016

Motion of microgels in electric fields.

J J Liétor-Santos¹, A Fernández-Nieves

¹School of Physics, Georgia Institute of Technology, Atlanta, GA 30332, USA.

Advances in Colloid and Interface Science

|September 16, 2008

Summary

The electrophoretic mobility of neutral microgels decreases with swelling, while charged microgels show increased mobility. This difference is due to electro-osmotic flows within charged microgels, altering their behavior in electric fields.

More Related Videos

The Mechanics of (Poro-)Elastic Contractile Actomyosin Networks As a Model System of the Cell Cytoskeleton

The Mechanics of (Poro-)Elastic Contractile Actomyosin Networks As a Model System of the Cell Cytoskeleton

Published on: March 10, 2023

Controlled Synthesis and Fluorescence Tracking of Highly Uniform Poly(N-isopropylacrylamide) Microgels

Controlled Synthesis and Fluorescence Tracking of Highly Uniform Poly(N-isopropylacrylamide) Microgels

Published on: September 8, 2016

Related Experiment Videos

Last Updated: Jul 1, 2026

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Published on: February 13, 2016

The Mechanics of (Poro-)Elastic Contractile Actomyosin Networks As a Model System of the Cell Cytoskeleton

The Mechanics of (Poro-)Elastic Contractile Actomyosin Networks As a Model System of the Cell Cytoskeleton

Published on: March 10, 2023

Controlled Synthesis and Fluorescence Tracking of Highly Uniform Poly(N-isopropylacrylamide) Microgels

Controlled Synthesis and Fluorescence Tracking of Highly Uniform Poly(N-isopropylacrylamide) Microgels

Published on: September 8, 2016

Area of Science:

Soft matter physics
Colloid science
Polymer science

Background:

Microgels are soft polymer networks swollen with solvent.
Their motion in electric fields (electrophoresis) is crucial for applications.
Existing models often treat microgels as simple spheres, overlooking internal dynamics.

Purpose of the Study:

To review experimental data on microgel electrophoresis.
To explain the differing electrophoretic behavior of neutral and charged microgels.
To elucidate the role of internal electro-osmotic flows in charged microgel electrophoresis.

Main Methods:

Review of existing experimental results.
Theoretical analysis of electro-osmotic fluid flow within microgels.
Comparison with models for permeable objects and soft particle electrophoresis.

Main Results:

Neutral microgels exhibit electrophoretic mobility that decreases with swelling.
Ionic microgels show electrophoretic mobility that increases with swelling.
Electro-osmotic flows within ionic microgels explain their distinct behavior.

Conclusions:

Electrophoresis of neutral microgels can be modeled as charged hard spheres.
Ionic microgels behave as free-draining polyelectrolytes in electric fields.
Internal fluid flow is key to understanding charged microgel electrophoresis.