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Effective measurement of knee alignment using AP knee radiographs
Alexandra N Colebatch1, Deborah J Hart, Guangju Zhai
1MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital, Southampton, United Kingdom. a_colebatch@hotmail.com
The Knee
|September 16, 2008
Summary
Standard AP knee radiographs offer reproducible and comparable measurements of knee alignment to full-limb radiographs (FLR). This accessible method aids in assessing malalignment as an osteoarthritis risk factor in clinical practice and research.
Area of Science:
- Orthopedics
- Radiology
- Biomedical Engineering
Background:
- Full-limb radiographs (FLR) are the gold standard for measuring knee alignment.
- Antero-posterior (AP) knee radiographs offer a more accessible, economical, and lower-radiation alternative.
Purpose of the Study:
- To compare the reproducibility and accuracy of knee joint axial alignment measurements between FLR and conventional AP knee radiographs.
Main Methods:
- Knee alignment was measured in 80 knees from 40 subjects using both FLR and weight-bearing AP knee radiographs.
- Reproducibility was assessed using intra-class correlation coefficients (ICC) and kappa statistics.
Main Results:
- Both FLR and AP radiographs demonstrated good intra-observer reproducibility (ICC=0.99).
- Mean alignment angles were comparable (FLR: 178.9°, AP: 179.0°).
- Good correlation was observed between FLR and AP measurements (ICC 0.87-0.92).
Conclusions:
- Standard AP knee radiographs provide reproducible and comparable knee alignment measurements to FLR.
- AP knee radiographs are suitable for large cohort studies and clinical practice to assess malalignment and osteoarthritis risk.

