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Updated: Jul 1, 2026

Contrast-Enhanced Subharmonic Aided Pressure Estimation (SHAPE) Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension
Published on: December 5, 2020
Emerging roles for contrast-enhanced ultrasound
1Central Ultrasound Department, Klinikum Region Hannover, Hannover, Germany. weskotthp@T-online.de
Contrast-enhanced ultrasound (CEUS) offers a sensitive, inexpensive tool for tumor ablation management and lesion characterization across various medical fields. Its applications extend from liver and renal diseases to cancer detection and vascular imaging, with numerous benefits yet to be fully realized.
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Contrast-enhanced ultrasound (CEUS) is an emerging imaging modality.
- Its diagnostic capabilities are being explored for various clinical applications.
Purpose of the Study:
- To review new and potential applications of CEUS in radiology.
- To highlight its role in disease management and diagnosis.
Main Methods:
- Literature review of current and prospective CEUS uses.
- Analysis of CEUS performance compared to other imaging modalities.
Main Results:
- CEUS shows sensitivity comparable to CT/MRI for liver lesions.
- It is valuable in characterizing renal cysts, infarction, and masses.
- Potential applications identified in rheumatology, oncology (breast, prostate, lung), and vascular diseases.
- CEUS aids in tumor ablation planning, navigation, and follow-up.
- It enhances transcranial examinations and sentinel lymph node detection.
Conclusions:
- CEUS is a versatile tool with broad diagnostic and therapeutic support potential.
- Its sensitivity, accuracy, and cost-effectiveness position it for expanded clinical use.
- Further exploitation of CEUS benefits in diverse medical fields is anticipated.
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