[Flow cytometric DNA content analysis in thyroid carcinoma]

DNA content and proportion of Phase S cells in 69 paraffin embedded thyroid tumors (15 adenomas and 64 adenocarcinomas) were analysed by flow cytometry. The results showed that 14/15 adenomas were diploid; DNA content was abnormal in 1 papillary adenoma (DNA index 1.14). In the 64 cases of adenocarcinomas, 53 were aneuploid and 11 near diploid. The DNA content and proportion of Phase S cells were closely related to degree of malignancy and prognosis.