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Updated: Jul 1, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Weight management in a cohort of Irish inpatients with serious mental illness (SMI) using a modular behavioural
Chris J Bushe1, Dermot McNamara, Cliff Haley
1Eli Lilly and Company Ltd, Adelaide Road, Dublin, Ireland. bushe_chris@lilly.com
Background:
Weight gain is commonly observed during psychotropic treatments for chronic forms of severe mental illness and is most rapid during the early treatment phases. All formats of behavioural weight intervention programmes have suggested that weight gain can be prevented or reversed in some patients. There is no data on these programmes in acutely unwell inpatients whom may be the major beneficiaries.
Methods:
A modular behavioural intervention programme (Solutions for Wellness) used in SMI outpatients since 2002 in Ireland has been adapted for inpatient use. Preliminary data is reported from 5 centres in Ireland.
Results:
In 47 inpatients the mean weight change was +0.26 kg (SD 2.02) with a median change of 0 kg. Mean follow-up was 23.7 (SD 21.6) days, and median 14 days (range 6-98 days). There was no difference in mean weight change in those patients involved for > 35 days compared with < 35 days (+0.26 kg; 0.25 kg; p = 0.5). Weight loss or maintenance was seen in 70% of patients.
Conclusion:
These preliminary data are supportive of the concept that acutely unwell inpatients with SMI may engage with a behavioural weight programme. Weight change observed contrasts with the significant weight gain often seen in most subjects. Further clinical trials are warranted.