Multimarker panel in patients admitted to emergency department: a comparison with reference methods
Damien Gruson1, Frédéric Thys, Jean Marie Ketelslegers
1Department of Endocrinology and Nutrition, Unit of Diabetes and Nutrition, Cliniques Universitaires St-Luc, Brussels, Belgium. gruson_damien@yahoo.fr
Objectives:
Point of care testing and multimarker panels are rapidly expanding in emergency departments. We determined the reliability of Short-of-Breath SOB panel in patients admitted for acute dyspnea and/or chest pain.
Design And Methods:
SOB D-dimer, BNP, cTnI, CK-MB and myoglobin assays were compared with references in 97 outpatients.
Results:
The correlation between SOB and references methods was acceptable, but with limited precision and accuracy.
Conclusions:
Diagnostic performances and cut-off values should be further validated before clinicians replace traditional cardio-respiratory biomarkers by the new SOB panel.
