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Updated: Jul 1, 2026

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
Published on: September 26, 2019
Colonic involvement in a patient with chronic lymphocytic leukaemia
P E T Arkkila1, H Nuutinen, F Ebeling
1Department of Gastroenterology, Helsinki University Central Hospital, 00290 Helsinki, Finland. perttu.arkkila@fimnet.fi
Abstract:
Various gastrointestinal infiltrations have been described in patients with chronic lymphocytic leukaemia (CLL). Here, we report a 69-year-old man with CLL and anaemia in whom the macroscopic finding of colonoscopy was normal, but the histological specimens revealed lymphocytic leukemia in ileum and in colon. If a CLL patient has any symptoms suggesting a possible GI manifestation of the haematologic disease or anaemia not explained by bone marrow infiltration or hemolysis, the diagnostic evaluation should include endoscopies with adequate biopsies.
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