Inattentive/overactive children with histories of profound institutional deprivation compared with standard ADHD

E J S Sonuga-Barke1, K Rubia

  • 1Developmental Brain-Behaviour Laboratory, School of Psychology, University of Southampton, Southampton, UK. ejb3@soton.ac.uk

Insights

Children with ADHD symptoms and early deprivation (D-I/OA) showed similar ADHD symptoms to clinical ADHD cases, but greater neuropsychological impairment. Girls with D-I/OA experienced symptom remission, unlike boys.

Area of Science:

  • Neuroscience
  • Child Psychology
  • Developmental Psychology

Background:

  • Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms, characterized by inattention/overactivity/impulsiveness (I/OA), are linked to early institutional care.
  • The English and Romanian Adoptees (ERA) study provides a unique cohort for examining the long-term effects of severe early deprivation.

Purpose of the Study:

  • To compare the symptom and neuropsychological profiles of children with a history of I/OA and early severe deprivation (D-I/OA) against standard clinical ADHD cases (S-ADHD) and deprivation-exposed controls (ERA-controls).
  • To investigate potential gender differences in ADHD symptom persistence and neuropsychological outcomes in children with a history of institutional care.

Main Methods:

  • Comparison of symptom and neuropsychological profiles in three groups: D-I/OA (n=13), S-ADHD (N=20), and ERA-controls (n=22).
  • Participants were assessed around age 13, with D-I/OA and ERA-controls drawn from the ERA study cohort.
  • Longitudinal data were analyzed to track symptom changes over time.

Main Results:

  • Male D-I/OA and S-ADHD cases exhibited similar ADHD symptom patterns.
  • Female D-I/OA cases showed symptom profiles more aligned with ERA controls, suggesting remission.
  • Neuropsychological assessments revealed greater impairment in both male and female D-I/OA children compared to S-ADHD and ERA controls.

Conclusions:

  • Children with D-I/OA demonstrate significant neuropsychological deficits irrespective of persistent ADHD symptoms, which were more evident in boys.
  • Gender differences in symptom persistence were observed, with girls showing remission.
  • Findings highlight the profound and persistent neuropsychological impact of early severe deprivation, even when overt ADHD symptoms diminish.
Abstract

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