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Related Experiment Video

Updated: Jun 30, 2026

Purification and Quality Control of Recombinant Septin Complexes for Cell-Free Reconstitution

Purification and Quality Control of Recombinant Septin Complexes for Cell-Free Reconstitution

Published on: June 23, 2022

The septal body revisited.

S Elwany¹, S A Salam, A Soliman

¹Department of Otolaryngology, Alexandria University, Egypt. samyelwany@msn.com

The Journal of Laryngology and Otology

|September 18, 2008

Summary

The septal body, a nasal septum structure, has unique histological features and defined dimensions. Understanding its characteristics is key to nasal airflow research.

Area of Science:

Otorhinolaryngology
Anatomy
Histology

Background:

The septal body is an understudied thickened area of the nasal septum.
It plays a role in nasal airflow resistance but is often misdiagnosed.
Its precise anatomical and histological features require further investigation.

Purpose of the Study:

To histologically characterize the septal body mucosa.
To identify morphometric differences between septal body mucosa and adjacent septal mucosa.
To precisely define the location and surface area of the septal body.

Main Methods:

Analysis of 30 cadaveric nasal septal specimens.
Histological staining (H&E, PAS-AB) and morphometric analysis.
Definition of septal body boundaries using a Mohs-technique-like approach.

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Purification and Quality Control of Recombinant Septin Complexes for Cell-Free Reconstitution

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Main Results:

Septal body mucosa features thick respiratory epithelium, goblet cells, seromucinous glands, and blood sinusoids.
It exhibits thicker epithelium, more glands, and sinusoids than surrounding mucosa.
Specific dimensions and location relative to nasal structures were mapped.

Conclusions:

The study precisely defined the septal body's morphometric characteristics, location, and surface area.
Its histological traits and proximity to the internal nasal valve warrant further research.
Investigating its role in nasal airflow, humidity, and temperature regulation is recommended.