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Sutures of the Skull

Sutures of the Skull

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

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Isolation and Culture of Dental Epithelial Stem Cells from the Adult Mouse Incisor

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Published on: May 1, 2014

Cementum analysis in cleidocranial dysostosis.

K Manjunath¹, B Kavitha, T R Saraswathi

¹Department of Oral and Maxillo-Facial Pathology, Meenakshi Ammal Dental College and Hospitals, Chennai - 600 095, India.

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research

|September 18, 2008

Summary

Cellular cementum absence does not impede tooth eruption in cleidocranial dysostosis (CCD). This study found other factors contribute to delayed eruption in CCD patients with dental anomalies.

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Area of Science:

Dental Anatomy
Skeletal Dysplasias
Tooth Eruption Biology

Background:

Cleidocranial dysostosis (CCD) is a genetic disorder causing skeletal and dental anomalies, including delayed or failed permanent tooth eruption and supernumerary teeth.
The role of apical cellular cementum in tooth eruption is debated, with some theories suggesting its absence contributes to eruption failures in CCD.

Observation:

This study examined root cementum in supernumerary and permanent teeth from a CCD patient compared to normal individuals.
Microscopic analysis focused on root characteristics, cemento-enamel junctions, and root resorption patterns.

Findings:

Absence of apical cellular cementum, increased root resorption, and a higher prevalence of gap-type cemento-enamel junctions were observed in CCD teeth.
Contrary to presumption, the absence of cellular cementum did not prevent eruption in the studied CCD teeth.

Implications:

The findings challenge the necessity of apical cellular cementum for tooth eruption, suggesting other mechanisms are at play in CCD.
Factors such as mechanical obstruction and reduced serum alkaline phosphatase levels may be more critical for eruption in CCD.
Further research is needed to elucidate the role of gap-type cemento-enamel junctions in tooth eruption dynamics.