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Severe acute pancreatitis: overall and early versus late mortality in intensive care units
Vesna Bumbasirevic1, Dejan Radenkovic, Zorica Jankovic
1Clinical Center of Serbia, Belgrade, Serbia.
Objectives:
To determine overall mortality and timing of death in patients with severe acute pancreatitis and factors affecting mortality.
Methods:
This was a retrospective, observational study of 110 patients admitted to a general intensive care unit (ICU) from January 2003 to January 2006.
Results:
The overall mortality rate was 53.6% (59/110); 25.4% (n = 15) of deaths were early (
Conclusions:
Overall mortality and median APACHE II score were high. Death predominantly occurred late and was unaffected by patient age, length of stay in the ICU, or surgical/medical treatment. An APACHE II cutoff of 24.5 and pre-ICU admission time of 2.5 days were sensitive predictors of fatal outcome.
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