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Related Concept Videos

Applications of Life Tables01:22

Applications of Life Tables

Life tables are versatile across various fields, providing a quantitative basis for analyzing mortality and survival rates. Whether used by demographers, actuaries, epidemiologists, or sociologists, life tables offer valuable insights into the dynamics of life and death, facilitating informed decisions in public health, insurance, conservation, and beyond. Their broad applicability highlights the interconnectedness of demographic data with practical outcomes in everyday life and strategic...
Life Tables01:22

Life Tables

A life table is a statistical tool that summarizes the mortality and survival patterns of a population, providing detailed insights into the likelihood of survival or death across different age intervals within a cohort. By organizing data on survival probabilities and mortality rates, life tables offer a clear snapshot of population dynamics over time. They are extensively used in demography, public health, actuarial science, and ecology to analyze life expectancy, design health interventions,...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration01:28

Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area. This equation is...
Actuarial Approach01:20

Actuarial Approach

The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...

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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
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Published on: January 19, 2024

Estimating child mortality due to diarrhoea in developing countries.

Cynthia Boschi-Pinto1, Lana Velebit, Kenji Shibuya

  • 1Child and Adolescent Health, World Health Organization, Geneva, Switzerland. pintoc@who.int

Bulletin of the World Health Organization
|September 18, 2008
PubMed
Summary

Diarrhoea caused an estimated 1.87 million deaths in children under five globally, with most occurring in African and South-East Asian regions. These estimates aid planning in data-scarce areas.

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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Area of Science:

  • Global child health epidemiology
  • Public health surveillance
  • Mortality estimation

Background:

  • Diarrhoea remains a leading cause of under-five mortality globally.
  • Accurate cause-of-death data is often lacking in low-resource settings.
  • Existing data may not adequately capture the burden of diarrhoeal diseases.

Purpose of the Study:

  • To estimate diarrhoea mortality in children under five at country, regional, and global levels.
  • To apply the Child Health Epidemiology Reference Group (CHERG) standard for mortality estimation.
  • To provide reliable data for public health interventions and planning.

Main Methods:

  • Conducted a systematic literature review of studies published since 1980 on under-five diarrhoea mortality.
  • Collected data on study and population characteristics.
  • Utilized a regression model to estimate diarrhoea mortality distribution in national populations.

Main Results:

  • Estimated 1.87 million global deaths from diarrhoea in children under five (19% of total child deaths).
  • WHO African and South-East Asia Regions account for 78% of these deaths (1.46 million).
  • 73% of diarrhoea deaths are concentrated in 15 developing countries.

Conclusions:

  • Lack of regular cause-of-death data hinders planning for diarrhoea control interventions.
  • The study's methods provide crucial country-level estimates for data-poor settings.
  • These estimates serve as vital alternatives for planning and evaluating child survival strategies.