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[Acute hypertrophic gastropathy of childhood]
H Miskin1, P Lebensart, E Granot
1Dept. of Pediatrics, Hadassah University Hospital, Jerusalem.
Insights
Acute hypertrophic gastropathy in children causes stomach protein loss and low albumin. This rare, benign condition in two 3-year-old girls resolved spontaneously within weeks.
Area of Science:
- Pediatric Gastroenterology
- Rare Diseases
- Gastrointestinal Disorders
Background:
- Acute hypertrophic gastropathy is a rare childhood condition.
- It presents with gastrointestinal issues and hypoalbuminemia due to gastric protein loss.
Observation:
- Two 3-year-old girls diagnosed with acute hypertrophic gastropathy were studied.
- Diagnostic workup included X-rays, abdominal ultrasound, and gastroscopy with biopsy.
Findings:
- Gastrointestinal protein loss was confirmed by fecal alpha 1 antitrypsin levels.
- Both patients demonstrated complete, spontaneous recovery within weeks.
Implications:
- This case series highlights the benign and self-limiting nature of acute hypertrophic gastropathy in children.
- Early diagnosis and supportive care are key for managing this rare condition.
Abstract:
Acute hypertrophic gastropathy of childhood is a rare disease characterized by gastrointestinal complaints and hypoalbuminemia due to protein loss from the stomach. The disease is benign, with complete recovery within a few months. We describe 2 girls with this condition, both 3 years old, in whom a detailed workup was performed, including upper gastrointestinal tract X-rays, ultrasound examination of the abdomen, and gastroscopy with mucosal biopsy. Gastrointestinal protein loss was demonstrated by measuring alpha 1 antitrypsin in the feces. Both children recovered spontaneously within a few weeks.