Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nephrons01:10

Nephrons

The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma happens...
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
Urinary Tract Calculi I: Introduction01:28

Urinary Tract Calculi I: Introduction

Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
Renal Corpuscle01:20

Renal Corpuscle

The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role of glucocorticoid metabolism in childhood obesity-associated hypertension.

Endocrine connections·2022
Same author

Is mid-upper arm circumference in Dutch children useful in identifying obesity?

Archives of disease in childhood·2018
Same author

Is There an Association Between Cortisol and Hypertension in Overweight or Obese Children?

Journal of clinical research in pediatric endocrinology·2017
Same author

Population Pharmacokinetics of Prednisolone in Relation to Clinical Outcome in Children With Nephrotic Syndrome.

Therapeutic drug monitoring·2016
Same author

Is the prevalence of hypertension in overweight children overestimated?

Archives of disease in childhood·2016
Same author

Screening, diagnosis and treatment of hypertension in obese children: an international policy comparison.

Journal of nephrology·2016

Related Experiment Video

Updated: Jun 30, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
06:27

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

Nephrocalcinosis in preterm neonates.

Eveline A Schell-Feith1, Joana E Kist-van Holthe, Albert J van der Heijden

  • 1Department of Pediatrics, Rijnland Ziekenhuis, Leiderdorp, The Netherlands.

Pediatric Nephrology (Berlin, Germany)
|September 18, 2008
PubMed
Summary
This summary is machine-generated.

Nephrocalcinosis (NC) affects 7-41% of preterm neonates, often resolving but potentially causing long-term kidney issues. Further research into prevention strategies is crucial for these vulnerable infants.

More Related Videos

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
03:19

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

Published on: June 21, 2024

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

Related Experiment Videos

Last Updated: Jun 30, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
06:27

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
03:19

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

Published on: June 21, 2024

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

Area of Science:

  • Neonatal Medicine
  • Pediatric Nephrology
  • Medical Imaging

Background:

  • Nephrocalcinosis (NC) prevalence in preterm neonates varies widely (7-41%) due to differing methodologies.
  • NC in neonates stems from multifactorial causes including prematurity, low birth weight, respiratory disease, and imbalanced stone factors.
  • Calcium oxalate crystals are implicated in neonatal NC, with spontaneous resolution in 85% of cases within early childhood.

Purpose of the Study:

  • To review the prevalence, etiology, and long-term consequences of nephrocalcinosis in preterm neonates.
  • To evaluate current understanding of NC pathogenesis and potential sequelae.
  • To highlight the need for improved prevention strategies and long-term follow-up.

Main Methods:

  • Literature review of studies on neonatal nephrocalcinosis.
  • Analysis of prevalence data, etiological factors, and histological findings.
  • Evaluation of long-term renal outcomes and blood pressure in preterm infants.

Main Results:

  • Prevalence of NC in preterm neonates ranges from 7% to 41%, influenced by study variations.
  • Prematurity is linked to hypertension, smaller kidneys, and tubular dysfunction, with NC potentially exacerbating these issues.
  • While NC often resolves, long-term renal and vascular sequelae are possible, necessitating monitoring.

Conclusions:

  • Long-term monitoring of blood pressure and renal function is recommended for preterm infants, particularly those with neonatal NC.
  • Current low-dose oral citrate for NC prevention shows limited efficacy, suggesting higher dosages warrant investigation.
  • Further research into effective NC prevention in preterm neonates is essential.