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Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
11:04

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

[The influence of glycemia on the left ventricular diastolic function in patients with arterial hypertension]

Suzana Milutinović1, Radovan Karadzić

  • 1Poliklinika "Varnava", Nis.

Medicinski Pregled
|September 19, 2008
PubMed

Insights

Diabetic patients with arterial hypertension show impaired left ventricular diastolic function. Higher glycemia levels correlate with longer deceleration times and reduced early-stage ventricular filling velocities.

Area of Science:

  • Cardiology
  • Diabetology
  • Echocardiography

Context:

  • Arterial hypertension impacts left ventricular diastolic function.
  • Diabetic cardiomyopathy mechanisms are debated, with potential roles beyond hypertension and atherosclerosis.
  • Glycemia's specific effect on diastolic function in hypertensive patients requires investigation.

Purpose:

  • To investigate the effect of glycemia on left ventricular diastolic function in patients with arterial hypertension.
  • To compare diastolic function parameters between hypertensive patients with and without diabetes mellitus.

Summary:

  • Sixty hypertensive patients (30 with diabetes) underwent Doppler echocardiography.
  • Hypertensive patients with diabetes exhibited higher obesity, glycemia, and left atrial volume.
  • Significant differences in diastolic function included longer deceleration time, lower early diastolic filling velocity, and lower early/late filling ratio in diabetic patients.

Impact:

  • Demonstrates significant alterations in diastolic function parameters in hypertensive patients with diabetes mellitus.
  • Highlights the influence of glycemia on cardiac diastolic function.
  • Provides echocardiographic evidence of diabetic cardiomyopathy in hypertensive individuals.
Abstract

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