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[Study on the distribution and location of neuroglobin in human tissues and cells]
Hao-jie Qin1, Lu-shun Zhang, Na Wu
1Department of Forensic Pathology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Objective:
To explore the distribution and location of neuroglobin (NGB) and its function in human tissues and cells.
Methods:
The distribution and localization of NGB in human tissues and cells were examined by immunohistochemical method.
Results:
NGB-positive cells were mainly distributed in neurons of central nervous system and peripheral nervous system, and some in endocrine tissues and genital system. NGB-immunoreactive product located in the cytoplasm of these cells.
Conclusion:
The expression of NGB in human nervous tissues, some endocrine tissues and genital system suggested that NGB might play an important role in the utilizations of oxygen and physiological functions.
