Related Experiment Video
Updated: Jun 30, 2026

07:30
Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
Published on: August 18, 2020
Does cannabis use lead to depression and suicidal behaviours? A population-based longitudinal study
1Department of Sociology and Human Geography, University of Oslo, Oslo, Norway. willy.pedersen@sosiologi.uio.no
Acta Psychiatrica Scandinavica
|September 19, 2008
Summary
Cannabis use in young adults is linked to increased suicide attempts and ideation, but not depression. This longitudinal study followed young Norwegians for 13 years, finding significant associations in their twenties.
Area of Science:
- Psychiatry
- Addiction Medicine
- Epidemiology
Background:
- Adolescent cannabis use is a public health concern.
- Understanding the long-term mental health consequences is crucial.
Purpose of the Study:
- To investigate the longitudinal relationship between cannabis use and depression, suicidal ideation, and suicide attempts.
- To examine these associations in a Norwegian youth cohort over 13 years.
Main Methods:
- Longitudinal study of 2033 Norwegians from early teens to late twenties.
- Data collection on cannabis exposure, depression, suicidal ideation, and attempts.
- Inclusion of confounding factors for adjusted analysis.
Main Results:
- No association between early adolescent cannabis use and later depression or suicidal behaviors.
- Significant associations observed in the twenties between cannabis use and suicide ideation/attempts.
- Adjusted odds ratio of 2.9 for suicide attempts in those using cannabis 11+ times.
Conclusions:
- Cannabis exposure alone does not appear to cause depression.
- Cannabis use is associated with increased risk of later suicidal thoughts and attempts in young adulthood.
Related Concept Videos
Stress and Mental Health
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
Longitudinal Research
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Long-term Depression
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Calcium Ion Concentration Mechanism
If over time, all...
Long-term Depression
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Depressive Disorders: Etiology
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Stress Prevention and Stress Management Techniques IV
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
