Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Spherical Tokamak for Energy Production: theme issue introduction.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2024

Same author

Nonlinear Kinetic Ion Response to Small Scale Magnetic Islands in Tokamak Plasmas: Neoclassical Tearing Mode Threshold Physics.

Physical review letters·2018

Same author

Nonlinear Stability and Saturation of Ballooning Modes in Tokamaks.

Physical review letters·2016

Same author

Explosive instability and erupting flux tubes in a magnetized plasma.

Proceedings. Mathematical, physical, and engineering sciences·2015

Same author

Fluorescence yields and molecular orientation of thin organic films: Vapor-Deposited Oligothiophenes α3T-α8T.

Journal of fluorescence·2013

Same author

Rapid, minimally invasive adult voluntary male circumcision: A randomised trial.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2013

Search research articles

Related Experiment Video

Updated: Jun 30, 2026

How to Create and Use Binocular Rivalry

How to Create and Use Binocular Rivalry

Published on: November 10, 2010

Binocular rivalry in migraine.

F Wilkinson¹, O Karanovic, H R Wilson

¹Centre for Vision Research, York University, Toronto, ON, Canada. franw@yorku.ca

Cephalalgia : an International Journal of Headache

|September 19, 2008

Summary

This summary is machine-generated.

Migraine patients show altered visual perception, not due to weak brain inhibition. Enhanced cortical excitation, possibly from eye input differences, may explain migraine visual symptoms.

More Related Videos

How to Build a Dichoptic Presentation System That Includes an Eye Tracker

How to Build a Dichoptic Presentation System That Includes an Eye Tracker

Published on: September 6, 2017

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

Related Experiment Videos

Last Updated: Jun 30, 2026

How to Create and Use Binocular Rivalry

How to Create and Use Binocular Rivalry

Published on: November 10, 2010

How to Build a Dichoptic Presentation System That Includes an Eye Tracker

How to Build a Dichoptic Presentation System That Includes an Eye Tracker

Published on: September 6, 2017

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

Area of Science:

Neuroscience
Ophthalmology
Neurology

Background:

Cortical hyperexcitability is implicated in migraine pathophysiology.
This hyperexcitability may stem from reduced inhibition or increased excitation within the cortex.

Purpose of the Study:

To investigate the underlying mechanisms of cortical hyperexcitability in migraine using binocular rivalry.
To differentiate between weakened intracortical inhibition and strengthened excitatory mechanisms in migraine.

Main Methods:

Binocular rivalry was employed to compare visual perception in migraine with aura (MA), migraine without aura (MoA), and control groups.
Participants viewed static oriented grating patterns, and dominance intervals of monocular percepts were analyzed.
Interocular differences in rivalry dominance durations and visual discomfort were assessed.

Main Results:

No significant evidence for weakened intracortical inhibition was found in either migraine group.
Migraine without aura (MoA) and migraine with aura (MA) groups showed significant and near-significant interocular differences in rivalry dominance, respectively, compared to controls.
Both MA and MoA groups reported significantly greater visual discomfort than controls.

Conclusions:

The findings do not support the hypothesis of weakened intracortical inhibition in migraine.
Enhanced recurrent cortical excitation, potentially influenced by precortical differences in visual input, offers a plausible explanation for migraine-related visual phenomena.
These results suggest a re-evaluation of migraine pathophysiology, focusing on excitatory mechanisms.