Isolation and genotype analysis of rubella virus from a case of Guillain-Barré syndrome
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Updated: Jun 30, 2026
Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
Published on: May 26, 2013
C A Figueiredo1, G B Klautau, A M S Afonso
1Instituto Adolfo Lutz, Seção de Vírus Produtores de Exantemas, Av. Dr. Arnaldo, 355, São Paulo, SP, 01246-902, Brazil. figueiredocris@uol.com.br
Abstract:
Rubella virus (RV) infection has sporadically been linked to Guillain-Barré syndrome (GBS), but the association with RV has been based only on clinical and/or serological backgrounds. In the present case it was possible to isolate RV (genotype 1a) from cerebrospinal fluid and peripheral blood mononuclear cells of an 18-year-old woman diagnosed with GBS after clinical manifestations of rubella. This report contributes to confirm RV as one of the triggering pathogens of this peripheral nervous system disease.
