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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

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Related Experiment Video

Updated: Jun 30, 2026

Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
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Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography

Published on: February 21, 2017

Energy-resolved computed tomography: first experimental results.

Polad M Shikhaliev1

  • 1Imaging Physics Laboratory, Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA 70803, USA. pshikhal@lsu.edu

Physics in Medicine and Biology
|September 19, 2008
PubMed
Summary

Energy-resolved computed tomography (CT) improves contrast-to-noise ratio (CNR) by weighting x-ray photon energies. This novel approach enhances material decomposition CT imaging for better diagnostic accuracy.

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Obtaining 3D Chemical Maps by Energy Filtered Transmission Electron Microscopy Tomography
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Last Updated: Jun 30, 2026

Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
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Published on: February 21, 2017

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Obtaining 3D Chemical Maps by Energy Filtered Transmission Electron Microscopy Tomography

Published on: June 9, 2018

Area of Science:

  • Medical Imaging
  • Photon Counting Detectors
  • Computed Tomography

Background:

  • Conventional CT systems use energy-integrating detectors, underestimating low-energy photons crucial for contrast.
  • Existing methods do not fully leverage the contrast information available from lower energy X-ray photons.

Purpose of the Study:

  • To report the first experimental results of energy-resolved computed tomography (CT).
  • To demonstrate the improvement in contrast-to-noise ratio (CNR) using X-ray energy weighting.
  • To evaluate the impact of energy weighting on material decomposition CT.

Main Methods:

  • Utilized a photon counting detector system with cadmium zinc telluride (CZT) semiconductor pixels.
  • Acquired energy-selective CT data from a cylindrical phantom with various contrast elements.
  • Applied digital X-ray energy weighting and material decomposition techniques to CT data.

Main Results:

  • Achieved significant CNR improvement for calcifications (1.40x) and iodine (1.63x) using X-ray energy weighting.
  • Enhanced CNR in material decomposition CT for calcification (1.57x) and iodine (1.46x).
  • Demonstrated feasibility of energy-weighted and material-selective CT imaging from a single scan.

Conclusions:

  • Energy-resolved CT with X-ray energy weighting offers a substantial improvement in CNR.
  • The technique shows promise for enhanced material decomposition in CT imaging.
  • Limitations due to detector artifacts (hole trapping, charge sharing) are identified, with ongoing research for solutions.