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Updated: Jun 30, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[General recommendations over perimenopausal transition therapy]
José Luis Neyro1, Camil Castelo Branco, Francisco Quereda
1Servicio de obstetricia y ginecología, Hospital de Cruces-Baracaldo, Universidad del País Vasco, UPV-EHU. doctor@neyro.com
Background:
Medical attention during perimenopause requires different therapeutic strategies.
Objective:
To define strategies for the attention of perimenopause women that can favor a healthy aging.
Methods:
Review of influencing factors and lifestyle modifications that can be introduced in perimenopause to prevent pathologies.
Results:
Diet composition and weight control influence cardiovascular and bone risks. It is difficult to get permanent changes in diet habits and there is a lack of conclusive evidence over the results of these recommendations, however there begin to arise better works that shows cardiovascular and osseous benefits of physical activity and specific exercise schedules. Due to them higher risk, it is necessary to suppress toxic habits. Several studies suggest phytotherapeutic supplements consumption benefit, however there is a lack of well-designed clinical essays to justify them recommendation.
Conclusions:
Correct nutritional state, appropriate diet, weight control, a common exercise practice, and suppression of toxic habits are applicable measures during perimenopause transition that could influence woman's health level for them lifespan. Individualized identification of diseases risk can justify the recommendations.
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