Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Stroke Volume01:27

Regulation of Stroke Volume

4.8K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
4.8K
Reaction Mechanisms03:06

Reaction Mechanisms

30.6K
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
30.6K
Mechanical Protein Functions01:58

Mechanical Protein Functions

5.5K
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 
5.5K
Acute Pharyngitis01:30

Acute Pharyngitis

4.0K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
4.0K
Arteries and Arterioles01:16

Arteries and Arterioles

6.4K
Arteries, the vasculature responsible for transporting blood from the heart, possess robust walls capable of enduring the elevated pressures exerted by the heartbeat. Arteries near the heart are especially thick-walled and enriched with elastic fibers across their three tunics, classifying them as elastic or conducting arteries. These arteries, usually with a diameter exceeding 10 mm, are characterized by their ability to dilate in response to the blood pumped from the heart's ventricles...
6.4K
Arteries of Lower Limbs01:20

Arteries of Lower Limbs

4.4K
The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular...
4.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is ophthalmology a pain-free career? A systematic review and meta-analysis of musculoskeletal pain among ophthalmologists.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same author

Middle Meningeal Artery Embolization With n-Butyl Cyanoacrylate in Patients With Chronic Subdural Hematoma: A Randomized Clinical Trial.

JAMA neurology·2026
Same author

Treatment-Related Factors Associated with Hemorrhagic Transformation and Hemorrhagic Subtypes after Mechanical Thrombectomy for Acute Ischemic Stroke.

AJNR. American journal of neuroradiology·2026
Same author

Clinical and Angiographic Outcomes in Patients With Tandem Occlusion Thrombectomy: Analysis From the ASSIST International Registry.

Stroke (Hoboken, N.J.)·2026
Same author

Neuroform Atlas stent-assisted coiling: jailing versus re-crossing techniques.

Journal of neurointerventional surgery·2026
Same author

Case Report of Malignancy-Hemophagocytic Lymphohistiocytosis: A Dangerous and Rare Sepsis Mimic.

The Journal of emergency medicine·2026

Related Experiment Video

Updated: Jan 23, 2026

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
07:34

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research

Published on: December 15, 2023

3.3K

Arterial vasospasm during mechanical thrombectomy for acute stroke.

Rishi Gupta1

  • 1Department of Neurology, Division of Cerebrovascular Diseases, Michigan State University, East Lansing, MI, USA. Rishi.gupta@ht.msu.edu

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
|September 20, 2008
PubMed
Summary

Mechanical thrombectomy for acute ischemic stroke can cause vasospasm, hindering recanalization. Prompt treatment with calcium channel blockers can resolve this complication, improving outcomes.

More Related Videos

Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery
07:26

Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery

Published on: May 24, 2021

8.2K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.5K

Related Experiment Videos

Last Updated: Jan 23, 2026

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
07:34

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research

Published on: December 15, 2023

3.3K
Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery
07:26

Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery

Published on: May 24, 2021

8.2K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.5K

Area of Science:

  • Neurology
  • Interventional Neuroradiology
  • Vascular Surgery

Background:

  • Mechanical thrombectomy is increasingly used for large artery occlusion in acute ischemic stroke.
  • Arterial vasospasm during endovascular procedures can impede successful recanalization.

Observation:

  • Two cases of significant, occlusive vasospasm at the L5 Merci retrieval device deployment site are reported.
  • The vasospasm affected a division of the middle cerebral artery in both patients.

Findings:

  • Infusion of calcium channel antagonists effectively resolved the arterial narrowing in both reported cases.
  • Vasospasm is a potential cause of poor recanalization after mechanical thrombectomy, especially when severe.

Implications:

  • Pharmacological treatment for vasospasm should be considered during endovascular revascularization for acute ischemic stroke.
  • Careful blood pressure monitoring is crucial when administering agents to treat vasospasm.
  • Understanding and managing procedure-induced vasospasm is vital for optimizing stroke treatment outcomes.