Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Papillary Dermis

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Reticular Dermis

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Arrhythmias and other cardiovascular diseases in young patients (<40 years) with moderate/severe atopic dermatitis: A multicentric study in northern Italy.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024

Same author

Effectiveness of guselkumab in patients with facial and/or genital psoriasis: Interim analysis results at Week 12 from the GULLIVER study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024

Same author

Consensus statement on the diagnosis and treatment of sclerosing diseases of the skin, Part 1: Localized scleroderma, systemic sclerosis and overlap syndromes.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024

Same author

Gender differences in adult atopic dermatitis and clinical implication: Results from a nationwide multicentre study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023

Same author

Shiitake flagellate dermatitis: a case series from Italy.

European annals of allergy and clinical immunology·2023

Same author

Single-nucleotide polymorphisms in 3'-untranslated region inducible costimulator gene and the important roles of miRNA in alopecia areata.

Skin health and disease·2022

Search research articles

Related Experiment Video

Updated: Jun 30, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

A unique case of multiple dermatomyofibromas.

G Viglizzo¹, C Occella, E Calonje

¹Department of Dermatology, IRCCS G Gaslini, Genoa, Italy.

Clinical and Experimental Dermatology

|September 20, 2008

Summary

This case study details multiple instances of dermatomyofibroma, a benign skin growth, found on a young boy's neck. This presentation is unusual as multiple lesions are rarely reported in medical literature.

More Related Videos

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Related Experiment Videos

Last Updated: Jun 30, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Area of Science:

Dermatology
Pediatric Pathology

Background:

Dermatomyofibroma is a benign skin neoplasm characterized by the proliferation of myofibroblasts.
This condition typically affects adolescents and young adults, with a noted predilection for females.
Dermatomyofibromas usually present as solitary lesions, such as plaques or nodules.

Observation:

A case of multiple dermatomyofibromas on the posterior neck of a 10-year-old male patient is described.
The lesions were noted to be multiple, differing from the typical solitary presentation.

Findings:

The histological examination confirmed the diagnosis of dermatomyofibroma.
The presence of multiple lesions in this pediatric case is a unique finding.

Implications:

This report expands the clinical spectrum of dermatomyofibroma presentation.
It highlights the importance of considering multiple lesions in the differential diagnosis, even in pediatric cases.
Further research may be warranted to understand potential triggers or genetic factors associated with multiple dermatomyofibromas.