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Related Concept Videos

Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Cells of the Epidermis01:24

Cells of the Epidermis

The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
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Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Seborrheic keratosis.

Christian Hafner1, Thomas Vogt

  • 1Clinic and Polyclinic for Dermatology, University of Regensburg, Germany. christian.hafner@klinik.uni-regensburg.de

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|September 20, 2008
PubMed
Summary
This summary is machine-generated.

Seborrheic keratosis is a common benign skin tumor. Recent molecular genetic research has shed light on its epidemiology, pathogenesis, diagnosis, and therapy, though many aspects remain unclear.

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Area of Science:

  • Dermatology
  • Oncology
  • Genetics

Background:

  • Seborrheic keratosis is a frequent benign epidermal tumor.
  • While not requiring treatment, lesions are often removed for cosmetic reasons.
  • Despite its prevalence, the underlying mechanisms of seborrheic keratosis are not fully understood.

Purpose of the Study:

  • To summarize current knowledge on seborrheic keratosis.
  • To highlight recent molecular genetic findings.
  • To cover epidemiology, pathogenesis, diagnosis, and therapy.

Main Methods:

  • Literature review of recent studies on seborrheic keratosis.
  • Synthesis of information on molecular genetics, epidemiology, pathogenesis, diagnosis, and treatment.
  • Focus on advancements in understanding the tumor.

Main Results:

  • New molecular genetic insights into seborrheic keratosis have emerged.
  • The review consolidates current understanding across key aspects.
  • Identifies areas where knowledge gaps persist.

Conclusions:

  • Seborrheic keratosis is a well-characterized benign tumor with ongoing research into its genetic basis.
  • Understanding pathogenesis and genetics may inform future diagnostic and therapeutic strategies.
  • Further research is needed to fully elucidate all aspects of this common skin condition.