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Updated: Jun 30, 2026

Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders
07:43

Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders

Published on: May 12, 2015

Genetic increase in brain-derived neurotrophic factor levels enhances learning and memory

Yukako Nakajo1, Susumu Miyamoto, Yoshikazu Nakano

  • 1Laboratory for Cerebrovascular Disorders, Research Institute of National Cardio-Vascular Center, Suita, Osaka 565-8565, Japan.

Brain Research
|September 20, 2008
PubMed
Summary

Increased brain-derived neurotrophic factor (BDNF) in heterozygous mice significantly enhanced spatial learning and memory. This suggests BDNF levels positively impact cognitive functions without affecting motor skills.

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