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Related Experiment Video

Updated: Jun 30, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

Comprehensive management for venous stasis ulcers.

Randy Shafritz¹, Laura Lamb-Susca, Alan M Graham

¹Division of Vascular Surgery, University of Medicine & Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.

Surgical Technology International

|September 20, 2008

Summary

Addressing venous stasis ulceration requires treating underlying venous hypertension. Surgical correction of venous hypertension, alongside standard treatments, improves healing and prevents recurrence.

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Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg

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Published on: November 19, 2019

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Last Updated: Jun 30, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg

Published on: November 19, 2019

Area of Science:

Vascular Surgery
Dermatology
Wound Care

Background:

Traditional venous stasis ulcer treatment includes compression, debridement, and topical care.
Pentoxifylline and bilayered living-cell therapy show efficacy in healing.
High recurrence rates persist despite initial healing, often attributed to noncompliance.

Observation:

Recurrence is frequently linked to uncorrected venous hypertension, a factor often overlooked in wound management.
Surgical correction of venous hypertension, such as saphenous stripping, has demonstrated improved ulcer healing rates.
Minimally invasive techniques now offer effective correction of venous pathology causing hypertension.

Findings:

Surgical intervention to correct venous hypertension significantly enhances ulcer healing.
Addressing the root cause of venous hypertension reduces ulcer recurrence rates.
Combined surgical and evidence-based wound care optimizes outcomes for venous stasis ulcers.

Implications:

Integrating surgical correction of venous hypertension into treatment protocols is crucial.
Minimally invasive venous procedures offer a viable solution for recurrent ulceration.
This approach promises better short-term healing and long-term prevention of venous stasis ulcers.