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Menstrual cycle phase and psychiatric admissions.
S D Targum1, K P Caputo, S K Ball
1Hahnemann University School of Medicine, PA.
Journal of Affective Disorders
|May 1, 1991
Summary
Psychiatric admissions significantly increase during the premenstrual and menstrual phases. These findings suggest late luteal phase biological changes can worsen psychiatric disorders in vulnerable individuals.
Area of Science:
- Psychiatry
- Gynecology
- Chronobiology
Background:
- Previous research indicates a link between the menstrual cycle and psychiatric admissions.
- The para-menstrual phase (premenstrual and menstrual periods) is often associated with increased psychiatric events.
Purpose of the Study:
- To investigate the association between menstrual cycle phase and emergency psychiatric admissions.
- To compare the menstrual cycle phase distribution of psychiatric patients with a control group.
Main Methods:
- Assessed menstrual cycle phase in 51 women admitted for emergency psychiatric care.
- Compared patient cycle phase distribution with 113 hospital staff controls assessed randomly.
- Utilized chi-squared tests to analyze phase distribution differences.
Main Results:
- 47% of psychiatric admissions occurred during the para-menstrual phase, compared to 22% in controls (P = 0.002).
- 33.3% of psychiatric admissions occurred within 4 days of menses onset.
- No significant differences were found based on psychiatric diagnosis, suicidality, or depression ratings.
Conclusions:
- Menstrual cycle entrainment and late luteal phase changes may exacerbate psychiatric disorders in vulnerable individuals.
- The effect appears independent of specific psychiatric diagnosis or severity indicators like depression ratings.