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Cutaneous mesenchymal hamartoma in the palm
M Takemiya1, H Ohtsuka, K Arashiro
1Department of Dermatology, Ehime University School of Medicine, Japan.
The Journal of Hand Surgery
|July 1, 1991
Summary
This report details a rare congenital solitary cutaneous mesenchymal hamartoma found on the palm. Mast cells were notably abundant, suggesting a potential role in this specific type of skin hamartoma.
Area of Science:
- Dermatopathology
- Surgical Pathology
- Pediatric Pathology
Background:
- Congenital mesenchymal hamartomas are rare benign tumors.
- Cutaneous mesenchymal hamartomas typically present as solitary lesions.
- This case focuses on a unique presentation in the palm.
Observation:
- A solitary congenital mesenchymal hamartoma was identified on the left palm.
- Histological examination revealed a mixture of fibrocollagenous tissue, mature fat, vascular structures, and eccrine glands.
- Numerous mast cells were dispersed throughout the fibrocollagenous stroma.
Findings:
- The hamartoma's composition included fibrocollagenous bundles, mature adipocytes, and smooth muscle-lined blood vessels.
- Eccrine sweat glands were present within the lesion.
- A significant presence of mast cells was a prominent feature of the observed hamartoma.
Implications:
- The mast cell's role in the pathogenesis of cutaneous mesenchymal hamartoma warrants further investigation.
- Understanding the cellular composition can aid in accurate diagnosis and management.
- This case contributes to the literature on rare pediatric skin tumors.