Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Network Covalent Solids

Network Covalent Solids

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...

Natural and Artificial Concepts

Natural and Artificial Concepts

In psychology, concepts can be divided into two categories: natural and artificial. Natural concepts are formed through direct or indirect experiences. For example, consider the concept of snow. If you live in a place with regular snowfall, such as Essex Junction, Vermont, you know snow through direct experiences. You’ve seen it fall, touched it, shoveled it, and played in it. You recognize its texture, appearance, and even its smell. In contrast, if you live on an island like Saint Vincent in...

Concepts and Prototypes

Concepts and Prototypes

The human nervous system handles vast amounts of information by translating sensory stimuli into neural impulses, which the brain processes, creating thoughts expressed through language or stored as memories. The brain also synthesizes information from emotions and memories, which significantly influence thoughts and behaviors. This intricate process creates a comprehensive mental picture.
The brain organizes this information using concepts, which are mental categories grouping linguistic data,...

Equity Theory

Equity Theory

Equity theory explains how our sense of fairness influences the dynamics of close relationships. Rooted in social psychology, the theory posits that individuals evaluate fairness by comparing the ratio of their contributions to the rewards they receive. Relationship satisfaction is highest when these ratios are perceived as balanced between partners, promoting mutual reciprocity and a sense of justice.Equity vs. Equality in RelationshipsEquity is distinct from equality. Fairness does not...

Design Consideration

Design Consideration

Designing a structure involves a series of considerations, primarily the material's ultimate strength, calculated through tests that measure changes under increased force until the material reaches its breaking point or limit. The ultimate load, where the material breaks, is divided by its original cross-sectional area, resulting in the ultimate normal stress or strength. The ultimate shearing stress is another significant factor taken into account.
The factor of safety is another key aspect...

Crystal Field Theory - Tetrahedral and Square Planar Complexes

Crystal Field Theory - Tetrahedral and Square Planar Complexes

Tetrahedral Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Older age and post-traumatic organ failure a TraumaRegister DGU<sup>®</sup> analysis of 34,469 elderly major trauma patients.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2026

Same author

Long-term clinical and radiological outcomes following non-union surgery: ongoing remodeling and improvement in clinical findings after five years.

Journal of orthopaedic surgery and research·2026

Same author

Genitourinary malignancy among patients presenting with microscopic hematuria in Northwestern Ontario.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada·2026

Same author

Surgically Treated Non-Unions and Fractures of the Femur and Tibia in Adults: A Nationwide Analysis of 888,442 Cases from the German InEK Database.

Journal of epidemiology and global health·2026

Same author

Interleukin-6 to identify mildly injured patients in the trauma resuscitation room - a clinical feasibility study.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2026

Same author

In-vitro evaluation of the proliferative and osteogenic activity of atrophic non-union derived mesenchymal stem cells compared to autologous bone graft derived mesenchymal stem cells.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2026

Search research articles

Related Experiment Video

Updated: Jun 30, 2026

$Synthesis and Microdiffraction at Extreme Pressures and Temperatures$

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

Published on: October 7, 2013

The diamond concept--open questions.

Peter V Giannoudis¹, Thomas A Einhorn, Gerhard Schmidmaier

¹Academic Department of Trauma and Orthopaedics, Leeds Teaching Hospitals, University of Leeds, UK. pgiannoudi@aol.com

|September 23, 2008

Summary

This summary is machine-generated.

Tissue engineering in orthopaedics advances tissue repair using cell-based methods. Further research is needed to clarify complex physiological processes for improved bone, cartilage, tendon, and ligament regeneration.

More Related Videos

Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis

Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis

Published on: January 6, 2016

$Characterization of Ultra-fine Grained and Nanocrystalline Materials Using Transmission Kikuchi Diffraction$

Characterization of Ultra-fine Grained and Nanocrystalline Materials Using Transmission Kikuchi Diffraction

Published on: April 1, 2017

Related Experiment Videos

Last Updated: Jun 30, 2026

$Synthesis and Microdiffraction at Extreme Pressures and Temperatures$

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

Published on: October 7, 2013

Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis

Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis

Published on: January 6, 2016

$Characterization of Ultra-fine Grained and Nanocrystalline Materials Using Transmission Kikuchi Diffraction$

Characterization of Ultra-fine Grained and Nanocrystalline Materials Using Transmission Kikuchi Diffraction

Published on: April 1, 2017

Area of Science:

Orthopaedic surgery
Regenerative medicine
Biomaterials science

Background:

Tissue engineering aims to regenerate bone, cartilage, tendon, and ligament.
Current strategies primarily utilize cell and tissue-based approaches.
The 'diamond concept' integrates growth factors, scaffolds, stem cells, and mechanical factors for fracture healing.

Purpose of the Study:

To discuss key unresolved issues in orthopaedic tissue engineering.
To identify areas requiring further clarification in regenerative medicine.
To advance the understanding of tissue repair and replacement strategies.

Main Methods:

Review of current tissue engineering principles.
Discussion of the 'diamond concept' components.
Identification of knowledge gaps in physiological processes.

Main Results:

Standard tissue engineering requires growth factors, scaffolds, mesenchymal stem cells, and mechanical environment.
Existing strategies benefit patients but raise further questions.
Several important issues in the field remain obscured.

Conclusions:

Continued research is essential to address complex physiological processes in tissue engineering.
Further clarification is needed to optimize treatments for bone, cartilage, tendon, and ligament repair.
Advancing orthopaedic regenerative medicine requires deeper understanding of underlying biological mechanisms.