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Related Experiment Video

Updated: Jun 30, 2026

A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side
09:58

A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side

Published on: May 6, 2016

[Choroid plexus carcinoma: a case report].

K Abbes1, A Khabir, K Bahloul

  • 1Laboratoire d'anatomie et de cytologie pathologique, CHU Habib-Bourguiba, route El-Aïn-Km-0,5, 3029 Sfax, Tunisie.

Neuro-Chirurgie
|September 23, 2008
PubMed
Summary
This summary is machine-generated.

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Choroid plexus carcinoma is a rare childhood brain tumor with a poor prognosis. Surgical removal is challenging due to its location and potential for severe bleeding.

Area of Science:

  • Pediatric neuro-oncology
  • Neurosurgery
  • Pathology

Background:

  • Choroid plexus carcinomas are rare intracranial neoplasms, predominantly affecting children.
  • Differential diagnosis includes choroid plexus papilloma and papillary ependymoma.
  • These tumors carry a generally poor prognosis.

Observation:

  • A 3-year-old presented with epilepsy and intracranial hypertension.
  • CT revealed an 11cm heterogeneously enhancing intracranial mass involving the ventricular system.
  • The patient experienced intraoperative hemorrhage and mortality following attempted resection.

Findings:

  • Histopathological examination confirmed choroid plexus carcinoma.
  • Radical surgical excision of choroid plexus carcinoma is technically demanding.

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Targeted Knockdown of Genes in the Choroid Plexus

Published on: June 16, 2023

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Last Updated: Jun 30, 2026

A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side
09:58

A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side

Published on: May 6, 2016

Targeted Knockdown of Genes in the Choroid Plexus
04:43

Targeted Knockdown of Genes in the Choroid Plexus

Published on: June 16, 2023

  • Significant intraoperative blood loss is a major risk associated with surgical intervention.

    • Implications:

    • Treatment strategies for choroid plexus carcinoma remain controversial.
    • Improved diagnostic and therapeutic approaches are needed for this rare pediatric malignancy.
    • Understanding the epidemiological characteristics and clinical presentation is crucial for timely diagnosis and management.