Disparities in use of same-day percutaneous coronary intervention for patients with ST-elevation myocardial infarction in Florida, 2001-2005
Elizabeth Barnett Pathak1, Joel A Strom
1Department of Epidemiology and Biostatistics, University of South Florida, Tampa, Florida, USA. ebarnett@health.usf.edu
Insights
Same-day primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) increased from 20% to 43% in Florida from 2001-2005. High-volume hospitals significantly improved PCI use, yet most STEMI patients still did not receive timely treatment.
Area of Science:
- Cardiology
- Health Services Research
Background:
- Primary percutaneous coronary intervention (PCI) is the guideline-recommended treatment for ST-elevation myocardial infarction (STEMI).
- Understanding predictors of same-day PCI is crucial for improving timely reperfusion therapy.
Purpose of the Study:
- To examine hospital and patient predictors of same-day primary PCI use for STEMI patients admitted through the emergency department (ED) in Florida.
- To assess trends in same-day PCI utilization from 2001 to 2005.
Main Methods:
- Analysis of inpatient discharge data for 58,308 adult STEMI patients admitted to Florida hospitals (2001-2005).
- Hierarchical (multilevel) logistic regression models were used to identify predictors of same-day PCI.
- Hospital PCI volume and individual patient characteristics were evaluated.
Main Results:
- Same-day PCI use increased from 20% in 2001 to 43% in 2005; at PCI-capable hospitals, it reached 50% by late 2005.
- Weekend admissions, female gender, older age (≥75), COPD, and ESRD were associated with lower odds of receiving same-day PCI.
- High- or medium-volume PCI-capable hospitals were the strongest predictor of same-day PCI (OR 4.6).
- Racial disparities in PCI use decreased over time, but men remained more likely to receive PCI than women.
Conclusions:
- Weekend admission, female gender, older age, and comorbidities are significant barriers to timely primary PCI for STEMI.
- Hospital PCI volume is a critical factor in increasing same-day PCI rates, independent of patient factors.
- Despite improvements, most ED-admitted STEMI patients in Florida did not receive primary PCI on the same day by 2005.
Abstract:
Primary percutaneous coronary intervention (PCI) is the recommended treatment for ST-elevation myocardial infarction (STEMI), according to American College of Cardiology and American Heart Association guidelines published in 1999 and 2004. In this study, hospital and patient predictors of same-day primary PCI use for STEMI were examined across the period from 2001 to 2005. Inpatient discharge data for adults aged > or =18 years with primary diagnoses of STEMI who were admitted to Florida hospitals through emergency departments (ED) from 2001 to 2005 (n = 58,308) were analyzed. Hierarchical (multilevel) logistic regression models were used to assess hospital PCI volume and individual characteristics as predictors of same-day PCI use for patients at PCI-capable hospitals. The percentage of ED-admitted patients with a STEMI who received same-day PCI in Florida increased from 20% in early 2001 to 43% in late 2005. At PCI-capable hospitals, 50% of these patients received same-day PCI in late 2005. Patients admitted on weekends, women, patients aged > or = 75 years, patients with chronic obstructive pulmonary disease, and patients with end-stage renal disease were all significantly less likely to receive same-day PCI. Black patients were less likely to receive same-day PCI in early 2001 (adjusted odds ratio [OR] 0.7, 95% confidence interval 0.5 to 0.9, p <0.0001), but this racial disparity was not evident by late 2005 (adjusted OR 1.0). Men were more likely than women to receive same-day PCI, with a significant association remaining in late 2005 (adjusted OR 1.2, 95% confidence interval 1.1 to 1.4, p <0.0001). Throughout the study period, the strongest predictor of same-day PCI was admission to a high- or medium-volume PCI-capable hospital; the adjusted OR in late 2005 was 4.6 (95% confidence interval 2.8 to 7.6, p <0.0001). In conclusion, weekend admission, female gender, older age, and serious co-morbidities were all significant barriers to receiving same-day PCI. Among patients admitted to PCI-capable hospitals, total PCI volume (high or medium vs low) was associated with significantly greater odds of receiving primary PCI, independent of patient sociodemographics, risk factors, or co-morbidities. Statewide, despite an increase in the use of PCI over time, most ED-admitted patients with a STEMI in Florida did not receive primary PCI in late 2005.
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