Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of protein lysine lactylation and potential targets in esophageal squamous cell carcinoma.

Translational cancer research·2026
Same author

The Ideal Number of Examined Lymph Node Stations for Accurate Nodal Staging and Prognosis in Pathological T1-2 Esophageal Squamous Cell Carcinoma: A Large-Scale Multicenter Cohort Study.

Annals of surgical oncology·2026
Same author

Transient Increase in AT<sub>1</sub>R Expression at the Myocardial Infarct Site Is Associated with Early Fibrotic Remodeling in Infarcted Rat Heart.

International journal of molecular sciences·2026
Same author

ASO Visual Abstract: Immunochemotherapy Versus Chemoradiotherapy Followed by Conversion Surgery for Initially Unresectable Stage cT4 Esophageal Squamous Cell Carcinoma.

Annals of surgical oncology·2026
Same author

Reply to: "Methodological Considerations on Prognostic Modeling in Esophageal Cancer-Commentary on Liu et al. (2026)".

Annals of surgical oncology·2026
Same author

Canadian Transplant Candidates' and Recipients' Perspectives on Mandatory Vaccination and Access to Transplantation: A Qualitative Study.

Clinical transplantation·2026
Same journal

A Health Tracking Application Leads to An Avid Cyclist Being Diagnosed with ALCAPA at 52 years old, Warranting a Takeuchi Repair.

The Annals of thoracic surgery·2026
Same journal

Impact of preoperative and postoperative modern guideline-directed medical therapy on survival following coronary artery bypass grafting.

The Annals of thoracic surgery·2026
Same journal

Does prior percutaneous coronary revascularization negatively affect the outcomes of subsequent coronary artery bypass grafting?

The Annals of thoracic surgery·2026
Same journal

Lymph Node Dissection and Chylothorax - Balancing Oncologic Benefit Against Morbidity.

The Annals of thoracic surgery·2026
Same journal

Preserved Antegrade Pulmonary Blood Flow in Bidirectional Glenn: Outcomes and Considerations for Staged Palliation.

The Annals of thoracic surgery·2026
Same journal

Domo Arigato, Mr. Roboto.

The Annals of thoracic surgery·2026
See all related articles

Related Experiment Video

Updated: Jun 30, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Late retrograde perfusion of donor lungs does not decrease the severity of primary graft dysfunction.

Pasquale Ferraro1, Jocelyne Martin, Julie Dery

  • 1Service de Chirurgie Thoracique, Département de Chirurgie, Centre de Recherche, Centre Hospitalier de l'Université de Montréal, Montréal, Quebec, Canada. pasquale.ferraro@umontreal.ca

The Annals of Thoracic Surgery
|September 23, 2008
PubMed
Summary
This summary is machine-generated.

Retrograde perfusion of donor lungs did not improve outcomes for primary graft dysfunction in lung transplantation. Standard antegrade preservation methods remain comparable to techniques involving retrograde perfusion.

More Related Videos

Cardiac Loading using Passive Left Atrial Pressurization and Passive Afterload for Graft Assessment
08:49

Cardiac Loading using Passive Left Atrial Pressurization and Passive Afterload for Graft Assessment

Published on: August 2, 2024

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
09:14

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Published on: October 18, 2024

Related Experiment Videos

Last Updated: Jun 30, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Cardiac Loading using Passive Left Atrial Pressurization and Passive Afterload for Graft Assessment
08:49

Cardiac Loading using Passive Left Atrial Pressurization and Passive Afterload for Graft Assessment

Published on: August 2, 2024

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
09:14

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Published on: October 18, 2024

Area of Science:

  • Thoracic Surgery
  • Transplantation Medicine
  • Organ Preservation

Background:

  • Establishing optimal preservation strategies for donor lungs is crucial in lung transplantation.
  • Primary graft dysfunction remains a significant challenge post-transplant.
  • This study evaluates novel perfusion techniques for lung preservation.

Purpose of the Study:

  • To compare the efficacy of antegrade versus retrograde lung perfusion in preventing primary graft dysfunction.
  • To assess the impact of different preservation solutions and perfusion methods on clinical outcomes.

Main Methods:

  • A 6-year clinical study involving 153 lung transplant recipients.
  • Three groups were compared: antegrade Euro-Collins, antegrade low-potassium dextran (LPD), and antegrade plus preimplantation retrograde LPD.
  • Key endpoints included acute lung injury (ALI) scores, ventilation duration, ICU stay, and survival rates.

Main Results:

  • Demographics, diagnoses, and ischemic times were similar across all groups.
  • No significant differences were observed in ALI scores or ventilation duration between the groups.
  • Length of ICU stay, operative mortality, and survival rates were also comparable.

Conclusions:

  • Late retrograde perfusion of donor lungs does not offer an advantage over standard antegrade techniques in reducing primary graft dysfunction.
  • Current antegrade preservation methods appear as effective as incorporating retrograde perfusion.