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Related Concept Videos

Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
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Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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The craniofacial muscles are a collection of approximately 20 thin skeletal muscles situated beneath the skin of the face and scalp. These muscles, primarily responsible for the vast array of human facial expressions, originate from the bones or fibrous structures of the skull and extend outwards to connect with the skin. While most skeletal muscles in the body are enveloped in thick fascia, facial muscles generally have a more delicate fascial covering, with the buccinator muscle being a...
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Satellite Stem Cells and Muscular Dystrophy

Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
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A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
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Related Experiment Video

Updated: Jun 30, 2026

Freezing Injury in Mouse Masseter Muscle to Establish an Orofacial Muscle Fibrosis Model
06:33

Freezing Injury in Mouse Masseter Muscle to Establish an Orofacial Muscle Fibrosis Model

Published on: December 29, 2023

Orofacial dysfunction in Duchenne muscular dystrophy.

Sébastien Botteron1, Catherine Morel Verdebout, Pierre-Yves Jeannet

  • 1Department of Orthodontics, University of Geneva, Switzerland. sebastien.botteron@medecine.unige.ch

Archives of Oral Biology
|September 23, 2008
PubMed
Summary
This summary is machine-generated.

Duchenne muscular dystrophy (DMD) impairs orofacial function, with reduced bite force linked to poorer masseter muscle quality in older patients. This highlights the importance of orofacial care as life expectancy increases.

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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

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Last Updated: Jun 30, 2026

Freezing Injury in Mouse Masseter Muscle to Establish an Orofacial Muscle Fibrosis Model
06:33

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Published on: December 29, 2023

Assessing Functional Performance in the Mdx Mouse Model
10:32

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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
09:18

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

Published on: January 12, 2019

Area of Science:

  • Neurology
  • Musculoskeletal Disorders
  • Biomedical Engineering

Background:

  • Duchenne muscular dystrophy (DMD) is a genetic disorder impacting muscle strength and function.
  • Orofacial function, including chewing and speaking, can be affected in individuals with DMD.
  • Understanding the progression of orofacial dysfunction in DMD is crucial for patient care.

Purpose of the Study:

  • To evaluate orofacial function in DMD patients.
  • To investigate the relationship between age, masseter muscle quality, and orofacial function deterioration in DMD.
  • To assess bite force and masseter muscle characteristics in DMD patients compared to controls.

Main Methods:

  • Bite force and finger force measurements were taken from 16 DMD patients and 16 age-matched controls.
  • Ultrasonography was used to assess masseter muscle thickness and internal structure quality.
  • Data analysis correlated orofacial function parameters with patient age and muscle quality.

Main Results:

  • DMD patients exhibited reduced mouth opening and lower bite force compared to controls.
  • No significant differences in masseter muscle thickness were observed between groups.
  • Poorer masseter muscle internal structure quality was found in older, non-walking DMD patients, correlating with reduced bite force.

Conclusions:

  • The masseter muscle's condition in DMD patients reflects the general disease progression.
  • Orofacial function decline in DMD is associated with age and diminished muscle quality.
  • Monitoring orofacial function is increasingly vital for DMD patients due to rising life expectancy.