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Updated: Jun 30, 2026

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
Published on: February 10, 2023
Single port sigmoidectomy in an experimental model with survival
Joel Leroy1, Ronan A Cahill, Silvana Peretta
1IRCAD/EITS, 1 Porte de l'Hôpital, Strasbourg, France.
Single port laparoscopic surgery for colonic resection and reanastomosis is feasible and safe in pigs. This approach may advance minimally invasive surgery and facilitate new endoscopic techniques.
Area of Science:
- Minimally Invasive Surgery
- Surgical Technology
- Gastrointestinal Surgery
Background:
- Single port laparoscopic access potentially reduces morbidity compared to multi-port techniques.
- Novel trocar technology is crucial for advancing single-port and natural orifice transluminal endoscopic surgery (NOTES).
Purpose of the Study:
- To evaluate the technical feasibility and safety of a novel single port system for laparoscopic sigmoid resection and reanastomosis in a porcine model.
Main Methods:
- A novel vortex-seal port was used for single-port laparoscopic sigmoid resection and reanastomosis in 6 pigs.
- Animals were observed for 2 weeks, followed by sigmoidoscopy and laparotomy to assess anastomotic healing and complications.
Main Results:
- The procedure was technically feasible with a mean operative time of 12.3 minutes.
- All animals survived, with patent anastomoses observed at follow-up; one required re-do due to staple misfire but was managed without additional ports.
- Only one animal showed complicated anastomotic healing, correlating with the re-do procedure.
Conclusions:
- Single port colonic resection and reanastomosis is readily achievable in this animal model.
- This approach may advance single-port surgery and facilitate the clinical adoption of other developmental access routes.
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