Related Experiment Video

Updated: Jun 30, 2026

Mapping Absolute DNA Density in Cell Nuclei using Single-molecule Localization Microscopy
10:57

Mapping Absolute DNA Density in Cell Nuclei using Single-molecule Localization Microscopy

Published on: November 11, 2025

Dynamic organization of gene loci and transcription compartments in the cell nucleus

James A Spudich1

  • 1Department of Biochemistry, Stanford University, Stanford, California, USA. jspudich@stanford.edu

Biophysical Journal
|September 23, 2008
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

In-Nucleus Hi-C in Drosophila Cells11:58

In-Nucleus Hi-C in Drosophila Cells

Published on: September 15, 2021

Getting an A with the 3Cs: Chromosome Conformation Capture for Undergraduates09:13

Getting an A with the 3Cs: Chromosome Conformation Capture for Undergraduates

Published on: May 12, 2023

Related Concept Videos

Chromatin Position Affects Gene Expression02:35

Chromatin Position Affects Gene Expression

Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the timing and level of...
Organization of Genes02:07

Organization of Genes

Overview
Organization of Genes02:07

Organization of Genes

Overview
DNA Packaging00:58

DNA Packaging

Overview
DNA Packaging00:58

DNA Packaging

Overview
The Nucleus01:25

The Nucleus

The nucleus is a membrane-bound organelle that acts as a control center in a eukaryotic cell. It contains chromosomal DNA, which controls gene expression and precisely regulates the production of proteins within the cell. In contrast, the DNA inside the mitochondria and chloroplast only carries out functions that are specific to those organelles.
Arrangement of DNA within Nucleus
The regulation of gene expression inside the nucleus is dependent on many factors, including the DNA structure. The...