Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Pituitary Gland01:17

The Pituitary Gland

The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Sinonasal Mucus Debridement on Nasal Nitric Oxide in Primary Ciliary Dyskinesia.

International forum of allergy & rhinology·2026
Same author

Assessing Olfactory Bulb Infiltration and Morphological Changes in Olfactory Neuroblastoma Using Magnetic Resonance Imaging.

Journal of neurological surgery. Part B, Skull base·2026
Same author

Concentric Tube Robot-Assisted Intracerebral Hemorrhage Evacuation: Validation in an Ovine Model.

IEEE transactions on medical robotics and bionics·2026
Same author

Modeling and Control For Minimally Invasive Intracerebral Hemorrhage Evacuation.

IEEE transactions on medical robotics and bionics·2026
Same author

Endoscopic Transnasal Approach for Deep Lateral Orbital Decompression: A Cadaver Study.

Journal of neurological surgery. Part B, Skull base·2026
Same author

Social Vulnerability and Quality of Life in Chronic Rhinosinusitis.

The Laryngoscope·2026

Related Experiment Video

Updated: Jun 30, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

Minimally invasive pituitary surgery.

Brent A Senior1, Charles S Ebert, Karen K Bednarski

  • 1Department of Otolaryngology-Head and Neck Surgery, Division of Rhinology, University of North Carolina at Chapel Hill, North Carolina 27599-7070, USA. cebert@med.unc.edu

The Laryngoscope
|September 23, 2008
PubMed
Summary
This summary is machine-generated.

Minimally invasive pituitary surgery (MIPS) using endoscopy offers a safe and effective approach. This technique provides excellent visualization and comparable outcomes to traditional methods with improved patient comfort.

More Related Videos

Minimally Invasive Surgical Decompression of Occipital Nerves
04:06

Minimally Invasive Surgical Decompression of Occipital Nerves

Published on: September 13, 2024

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
02:22

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Related Experiment Videos

Last Updated: Jun 30, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

Minimally Invasive Surgical Decompression of Occipital Nerves
04:06

Minimally Invasive Surgical Decompression of Occipital Nerves

Published on: September 13, 2024

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
02:22

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Area of Science:

  • Neurosurgery
  • Endoscopic Surgery
  • Pituitary Surgery

Background:

  • Surgical techniques for pituitary tumors have evolved significantly over the past century.
  • The integration of endoscopy has led to the development of minimally invasive pituitary surgery (MIPS).

Purpose of the Study:

  • To compile and evaluate the outcomes of all MIPS procedures performed at our institution.
  • To assess the safety and efficacy of MIPS in pituitary tumor resection.

Main Methods:

  • A retrospective case series analysis of 176 consecutive patients undergoing MIPS.
  • Demographic data, tumor characteristics, and intraoperative/postoperative complications were collected.
  • Statistical analyses, including Pearson's chi test and Fisher's exact tests, were used to determine complication rates and risk factors.

Main Results:

  • 193 procedures were performed on 176 patients, with 147 tumors being pituitary adenomas.
  • The overall mortality rate was low (0.5%), with one death.
  • Complication rates included diabetes insipidus (20.2%), vascular complications (5.2%), and cerebrospinal fluid (CSF) leaks (19.7% intraoperative, 10.3% postoperative).
  • Resection of non-adenoma tumors (OR = 9.0) and Rathke's cleft cysts (OR = 2.6) were associated with higher risks of CSF leaks.

Conclusions:

  • MIPS, combining endoscopy with the transsphenoidal approach, is safe and effective.
  • It offers enhanced visualization and the ability to explore the tumor bed with angled views.
  • MIPS achieves outcomes comparable to traditional methods with reduced tissue manipulation and improved patient comfort.