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Related Experiment Video

Updated: Jun 30, 2026

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Published on: March 31, 2023

Intratarsal epidermal inclusion cyst.

Mark J Lucarelli¹, Hee Bae Ahn, Amol D Kulkarni

¹Oculoplastics Service, University of Wisconsin-Madison, Madison, Wisconsin 53792, USA.

Ophthalmic Plastic and Reconstructive Surgery

|September 23, 2008

Summary

Three cases of epidermal inclusion cysts originating in the tarsus, an unusual location, were identified. These intratarsal cysts, initially mistaken for chalazia, required complete excision for effective treatment.

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Area of Science:

Ophthalmology
Dermatology
Pathology

Background:

Epidermal inclusion cysts are typically found in the dermis.
The tarsus is an unusual anatomical site for epidermal inclusion cyst development.

Observation:

Three cases of intratarsal epidermal inclusion cysts were identified over a decade.
These cysts initially presented with symptoms similar to chalazia.
Incision and curettage resulted in recurrence in all three cases.

Findings:

Histopathology confirmed keratin-filled cysts lined by stratified keratinized epithelium arising from the tarsus.
Cysts measured 8-10 mm and contained gelatinous material.
Complete excision of the cyst with surrounding tarsus prevented recurrence.

Implications:

Intratarsal epidermal inclusion cysts can mimic chalazia, necessitating careful differentiation.
Incision and curettage is an ineffective treatment for these tarsal cysts.
Surgical excision of the cyst and involved tarsus is recommended for definitive management.