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Related Experiment Video

Updated: Jun 30, 2026

A Standardized Surgical Technique for Tessier Medial Transnasal Canthopexy
06:08

A Standardized Surgical Technique for Tessier Medial Transnasal Canthopexy

Published on: January 23, 2026

Medial canthal tophus.

David R Jordan1, Michel J Belliveau, Seymour Brownstein

  • 1Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa, Ontario, Canada. jordan1897@rogers.com

Ophthalmic Plastic and Reconstructive Surgery
|September 23, 2008
PubMed
Summary
This summary is machine-generated.

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The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...

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A rare case of gouty tophi mimicking basal cell carcinoma in the eyelid is presented. This highlights the importance of considering gout in the differential diagnosis of periocular lesions.

Area of Science:

  • Ophthalmology
  • Dermatology
  • Rheumatology

Background:

  • Periocular lesions often require differential diagnosis between neoplastic and inflammatory conditions.
  • Basal cell carcinoma is a common skin malignancy presenting with diverse clinical features.

Observation:

  • A 68-year-old man presented with a suspicious medial canthal lesion resembling basal cell carcinoma.
  • The lesion was raised, nodular, skin-colored, with a pearly border and central depression.

Findings:

  • Excisional biopsy revealed a granulomatous inflammatory process consistent with gout.
  • The patient had a known history of gout with prior tophi on his elbows.

Implications:

  • Gouty tophi are exceptionally rare in the periocular region.

Related Experiment Videos

Last Updated: Jun 30, 2026

A Standardized Surgical Technique for Tessier Medial Transnasal Canthopexy
06:08

A Standardized Surgical Technique for Tessier Medial Transnasal Canthopexy

Published on: January 23, 2026

  • This case underscores the need to include gout in the differential diagnosis of clinically ambiguous eyelid lesions.