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Lyotropic liquid crystals and the structural lipids of the stratum corneum
I Kayali1, T Suhery, S E Friberg
1Chemistry Department, Clarkson University, Potsdam, N.Y. 13699.
Abstract:
Lipids were extracted from human stratum corneum and the remaining corneocytes were reaggregated with different lyotropic liquid crystals. Water transport through the reaggregated stratum corneum was determined using a diffusion chamber according to Smith and Blank. The permeability constant for the reaggregated stratum corneum with natural lipids was 25-40% lower than that with the surfactant liquid crystals, but there was no significant difference between different liquid crystals.
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