[Critical massive blood transfusion--O type and variant conformity blood transfusion]

Variant conformity blood is often used in transfusion at massive unpredictable hemorrhage under an operation or at hemorrhagic shock in a lifesaving emergency arena. This is because of difficulty in performing blood grouping, because of difficulty in deciding blood types in the laboratory, or because of lack in store of the same blood type transfusion as a pharmaceutical preparation needed for the patients. In performing variant conformity transfusion in the hospital, it is vitally important that in-house system be well-organized and staff be thoroughly informed about variant conformity transfusion. This chapter explains system arrangements of organization for variant conformity transfusion in hospital settings based on our experience in the urgent use of O type RCC-LR (Red Cells Concentrates-Leukocytes Reduce, "Nisseki") pharmaceutical preparation.