Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neural Circuits01:25

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Graded Potential01:19

Graded Potential

Graded potentials are localized fluctuations in the cell membrane's electrical charge, commonly found in the dendrites of neurons. The magnitude of these potential changes depends on the strength of the initiating stimulus. In a membrane at its resting potential, a graded potential signifies a voltage shift either above -70 mV or below -70 mV.
Graded potentials fall into two categories: depolarizing and hyperpolarizing. Depolarizing graded potentials typically occur when sodium (Na+) or calcium...
Excitatory and Inhibitory Effects of Neurotransmitters01:29

Excitatory and Inhibitory Effects of Neurotransmitters

When an action potential reaches the presynaptic axon terminal, it releases neurotransmitters from the neuron into the synaptic cleft at a chemical synapse. The released neurotransmitter can be excitatory or inhibitory. The critical criteria commonly used to determine whether a molecule is a neurotransmitter at a chemical synapse are the molecule's presence in the presynaptic neuron. Second, its release is in response to strong presynaptic depolarization. And lastly, the presence of specific...
Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Resting Potential Decay01:15

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane through...
Resting Potential Decay01:15

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane through...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of a central CGRP circuit for trigeminal V1-mediated migraine-like pain in mice.

Brain : a journal of neurology·2026
Same author

Sexually dimorphic mediation of experimental post-traumatic headache by orexin receptor signaling.

Pain·2026
Same author

Dual Roles of Voltage-gated Calcium Channels and γ-Aminobutyric Acid-mediated Signaling in Modulating Neurotensin Receptor Type 2-induced Antinociception.

Anesthesiology·2026
Same author

Sex-dependent central amygdala physiology after supradural CGRP exposure is associated with migraine-like behaviors.

The journal of headache and pain·2026
Same author

Kappa opioid receptor availability correlates with depressive symptom burden in chronic migraine: a preliminary investigation.

The journal of headache and pain·2026
Same author

Can new understanding of sexually dimorphic pain mechanisms provide a path to improved postoperative pain outcomes in women?

Pain·2026
Same journal

Preface.

Handbook of clinical neurology·2026
Same journal

Foreword.

Handbook of clinical neurology·2026
Same journal

Fundus autofluorescence imaging.

Handbook of clinical neurology·2026
Same journal

The electroretinogram as a means to study the physiology of the retina.

Handbook of clinical neurology·2026
Same journal

Adaptive optics scanning light ophthalmoscopy.

Handbook of clinical neurology·2026
Same journal

Modeling the human retina in a dish: Advances and future directions.

Handbook of clinical neurology·2026
See all related articles

Related Experiment Video

Updated: Jun 30, 2026

A Computer-assisted Multi-electrode Patch-clamp System
11:01

A Computer-assisted Multi-electrode Patch-clamp System

Published on: October 18, 2013

Chapter 14 Descending excitatory systems

Michael H Ossipov, Frank Porreca

    Handbook of Clinical Neurology
    |September 24, 2008
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    The Preparation of Oblique Spinal Cord Slices for Ventral Root Stimulation
    09:10

    The Preparation of Oblique Spinal Cord Slices for Ventral Root Stimulation

    Published on: October 13, 2016

    Examining Monosynaptic Connections in Drosophila Using Tetrodotoxin Resistant Sodium Channels
    09:55

    Examining Monosynaptic Connections in Drosophila Using Tetrodotoxin Resistant Sodium Channels

    Published on: February 14, 2018

    Related Experiment Videos

    Last Updated: Jun 30, 2026

    A Computer-assisted Multi-electrode Patch-clamp System
    11:01

    A Computer-assisted Multi-electrode Patch-clamp System

    Published on: October 18, 2013

    The Preparation of Oblique Spinal Cord Slices for Ventral Root Stimulation
    09:10

    The Preparation of Oblique Spinal Cord Slices for Ventral Root Stimulation

    Published on: October 13, 2016

    Examining Monosynaptic Connections in Drosophila Using Tetrodotoxin Resistant Sodium Channels
    09:55

    Examining Monosynaptic Connections in Drosophila Using Tetrodotoxin Resistant Sodium Channels

    Published on: February 14, 2018