Related Experiment Video
Updated: Jun 30, 2026
13:35
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Nipple-sparing mastectomy--initial experience at a tertiary center
Nicole Sookhan1, Judy C Boughey, Molly F Walsh
1Department of Surgery, Mayo Clinic, Rochester, MN, USA.
American Journal of Surgery
|September 24, 2008
Summary
Nipple-sparing mastectomy (NSM) offers a safe oncoplastic approach for breast cancer treatment. Initial outcomes show NSM is achievable with low morbidity in selected patients, preserving nipple-areolar complexes.
Area of Science:
- Oncoplastic Surgery
- Breast Surgery
- Surgical Oncology
Background:
- Nipple-sparing mastectomy (NSM) involves skin-sparing mastectomy with nipple-areolar preservation.
- Intraoperative pathologic assessment of the nipple core is integral to NSM.
- This study evaluates initial clinical outcomes of NSM.
Purpose of the Study:
- To assess the clinical outcomes of nipple-sparing mastectomy.
- To determine the feasibility and safety of NSM in a clinical setting.
Main Methods:
- Retrospective review of patients undergoing NSM.
- Data collected from November 2005 to June 2007.
- Institutional Review Board approval obtained.
Main Results:
- Eighteen NSM and two areola-sparing mastectomies were performed.
- Indications included invasive cancer, DCIS, hyperplasia, and risk reduction.
- Mean follow-up was 10.8 months with intact nipple-areolar complexes and no recurrences.
Conclusions:
- Nipple-sparing mastectomy is a viable surgical option.
- NSM can be successfully performed with low morbidity.
- Appropriate patient selection is key for successful NSM outcomes.
