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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Is the aortic root dilated in obstructive sleep apnoea syndrome?
Catherine Meuleman1, Franck Boccara, Xuan-Lan Nguyen
1Department of Cardiology, Saint-Antoine University and Medical School, Université Pierre-et-Marie-Curie, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France.
Archives of Cardiovascular Diseases
|September 24, 2008
Summary
Obstructive sleep apnoea syndrome (OSAS) does not increase aortic root size. Age and sex, not arterial hypertension, were linked to aortic dilatation in patients with OSAS.
Area of Science:
- Cardiology
- Sleep Medicine
- Vascular Biology
Background:
- Obstructive sleep apnoea syndrome (OSAS) is linked to cardiovascular diseases.
- The impact of OSAS on aortic root dimensions remains under-investigated.
- This study aimed to assess aortic root diameter and stiffness in OSAS patients.
Purpose of the Study:
- To investigate the relationship between OSAS and aortic root diameter.
- To evaluate aortic stiffness in individuals with OSAS.
- To identify predictors of aortic root dilatation in this population.
Main Methods:
- 76 patients with OSAS underwent transthoracic Doppler echocardiography.
- Aortic diameter, aortic regurgitation, left ventricular parameters, and pulmonary artery pressure were measured.
- Carotid-femoral pulse wave velocity was used to assess aortic stiffness.
Main Results:
- The prevalence of aortic root dilatation was 3.9% in the study cohort.
- Mean aortic root diameter was 35.3 +/- 3.8 mm.
- Univariate analysis revealed age and sex as significant predictors of aortic root dilatation, but not arterial hypertension.
Conclusions:
- Aortic root enlargement is not more prevalent in patients with OSAS.
- Age and sex are associated with aortic dilatation, independent of OSAS.
- Arterial hypertension was not found to be a predictor of aortic dilatation in this cohort.
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