Perinatal outcome after multifetal pregnancy reduction.
Seshadri Suresh1, Suresh Indrani, Gurusamy Thangavel
1Fetal Care Research Foundation, 197, Dr. Natesan road, Mylapore, Chennai, 600 004, India.
Indian Journal of Pediatrics
|September 24, 2008
Summary
Multifetal pregnancy reduction in India shows outcomes comparable to global studies, with notable rates of pregnancy loss and premature deliveries. Higher loss to follow-up was observed in this Indian cohort.
Area of Science:
- Reproductive Medicine
- Maternal-Fetal Medicine
- Obstetrics
Background:
- Multifetal pregnancies present increased risks to both mother and fetuses.
- Selective fetal reduction is a procedure to improve perinatal outcomes in high-order multiples.
Purpose of the Study:
- To evaluate the outcomes of multifetal pregnancy reduction (MFPR) in the Indian population.
- To compare these outcomes with international data.
Main Methods:
- Retrospective descriptive study analyzing data from 92 multifetal pregnancies undergoing fetal reduction.
- Standardized protocol for fetal reduction procedures was employed.
Main Results:
- Pregnancy loss occurred in 20.3% of cases (8.5% complete, 11.8% partial).
- Premature deliveries were observed in 35.6% of pregnancies.
- Median birth weight was 2100 grams, with 4 neonates born with congenital anomalies.
Conclusions:
- Perinatal outcomes, including median birth weight, pregnancy loss, and prematurity, are comparable to other international studies.
- A higher rate of loss to follow-up was identified in this Indian study cohort.

