Related Experiment Video
Updated: Jun 30, 2026
08:05
Candida albicans Biofilm Chip (CaBChip) for High-throughput Antifungal Drug Screening
Published on: July 18, 2012
Candida albicans adhesion to composite resin materials
Ralf Bürgers1, Wulf Schneider-Brachert, Martin Rosentritt
1Department of Prosthetic Dentistry, Regensburg University Medical Centre, Franz-Josef-Strauss-Allee, 93042 Regensburg, Germany. ralf.buergers@klinik.uni-regensburg.de
Clinical Oral Investigations
|September 24, 2008
Summary
This study compared how well Candida albicans adheres to 14 dental composite materials. Compomers and ormocers showed less fungal adhesion than conventional hybrid composites, with no clear link to surface properties.
Area of Science:
- Dental Materials Science
- Mycology
- Biomaterials
Background:
- Candida albicans adhesion to dental materials can lead to oral candidosis.
- Understanding material susceptibility is crucial for preventing fungal infections in the oral cavity.
Purpose of the Study:
- To compare the adhesion of Candida albicans to 14 different dental composite materials.
- To investigate the relationship between fungal adhesion and material surface properties (roughness, hydrophobicity).
Main Methods:
- Fourteen composite resin materials were tested for Candida albicans adhesion.
- Surface roughness and hydrophobicity were measured.
- Fungal adhesion was quantified using a bioluminometric assay.
Main Results:
- Compomers and ormocer materials exhibited significantly lower Candida albicans adhesion compared to conventional hybrid composites.
- Surface roughness (R(a)) ranged from 0.04 to 0.23 microm.
- Contact angles ranged from 69.2 to 86.9 degrees.
Conclusions:
- Compomers and ormocer demonstrate reduced susceptibility to Candida albicans adhesion.
- No definitive correlation was established between surface roughness, hydrophobicity, and fungal adhesion levels.
