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Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
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Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Ventilatory Modes01:14

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
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Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Anatomy of the Circulatory System02:03

Anatomy of the Circulatory System

The human circulatory system consists of blood, blood vessels that carry blood away from the heart, around the body, and back to the heart, and the heart itself, which acts as a central pump. The systemic circuit supplies blood to the whole body, the coronary circuit supplies blood to the heart, and the pulmonary circuit supplies blood flow between the heart and lungs.

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Related Experiment Video

Updated: Jun 30, 2026

The Intra-Aortic Balloon Pump
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Published on: February 5, 2021

Mechanical circulatory support: a clinical reality.

Daniel Loisance1

  • 1Hôpital Henri Mondor, Service de Chirurgie Thoracique et Cardiovasculaire, 51 Avenue du Maréchal de Lattre de Tassigny, 94010, Créteil Cedex, France. daniel.loisance@wanadoo.fr

Asian Cardiovascular & Thoracic Annals
|September 25, 2008
PubMed
Summary

Mechanical circulatory support devices offer a viable alternative for patients with severe heart failure. These ventricular assist devices provide crucial support, acting as a bridge to transplant or offering long-term solutions.

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Last Updated: Jun 30, 2026

The Intra-Aortic Balloon Pump
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Published on: February 5, 2021

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
08:49

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Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Area of Science:

  • Cardiology
  • Medical Engineering
  • Cardiac Surgery

Background:

  • Mechanical circulatory support (MCS) is an emerging therapeutic option for patients with cardiogenic shock or advanced cardiac failure unresponsive to maximal medical therapy.
  • Over three decades of research have enhanced the efficacy and reliability of ventricular assist devices (VADs).
  • VADs are increasingly promoted for managing complex cardiac conditions.

Purpose of the Study:

  • To highlight the role of VADs as a therapeutic option for advanced cardiac failure.
  • To discuss the applications of VADs, including bridging to transplantation, supporting native cardiac recovery, and permanent support.
  • To emphasize the need for precise prospective trials to optimize patient selection and timing for VAD utilization.

Main Methods:

  • Review of engineering development and clinical research in mechanical circulatory support.
  • Analysis of the current applications and benefits of ventricular assist devices.
  • Discussion of recent advancements and future directions in the field.

Main Results:

  • Ventricular assist devices have achieved significant efficacy and reliability.
  • A wide variety of devices are available, making MCS accessible to various cardiac surgical units.
  • Recent developments with implantable pumps indicate a transition from the pioneering phase to a more refined clinical application.

Conclusions:

  • Mechanical circulatory support, particularly VADs, provides a vital therapeutic strategy for end-stage heart failure.
  • The accessibility and versatility of VADs allow for diverse clinical applications, including in centers without established cardiac transplantation programs.
  • The field is advancing towards optimized patient selection and utilization timing through rigorous prospective trials.