Related Experiment Video
Updated: Jun 30, 2026

In Vitro Assay to Evaluate the Impact of Immunoregulatory Pathways on HIV-specific CD4 T Cell Effector Function
Published on: October 15, 2013
Hyper interleukin-10 in an HIV-positive child with t-cell lymphoma and candidal sepsis
Jennifer Lighter1, Doris B Tse, Aditya Kaul
1Saul Krugman Division of Pediatric Infectious Diseases and Immunology, New York University School of Medicine, New York, New York. lightj03@med.nyu.edu
Abstract:
We describe a case in which a human immunodeficiency virus (HIV)-positive child presented in severe metabolic acidosis secondary to his candidal sepsis and T-cell lymphoma, a rare finding in pediatric AIDS. Significantly elevated levels of Interleukin-10 (IL-10) were found in the patient's serum, which may have played a role in acute demise.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
