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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...

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Updated: Jun 30, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

LASIK and the ocular surface.

Ikuko Toda1

  • 1Minamiaoyama Eye Clinic, Tokyo, Japan. ikuko@tka.att.ne.jp

Cornea
|October 1, 2008
PubMed
Summary

LASIK eye surgery can disrupt ocular surface homeostasis, leading to complications like diffuse lamellar keratitis and epithelial ingrowth. Prompt management of these post-LASIK conditions is crucial for visual recovery.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Ocular Surface Disease

Background:

  • LASIK (Laser-Assisted In Situ Keratomileusis) can impact the ocular surface's delicate balance.
  • Post-LASIK complications require understanding for effective patient management.

Purpose of the Study:

  • To review common complications following LASIK surgery.
  • To discuss the etiology, presentation, and management of these conditions.

Main Methods:

  • Literature review of post-LASIK complications.
  • Analysis of inflammatory and regenerative processes affecting the cornea.

Main Results:

  • Diffuse lamellar keratitis, epithelial ingrowth, recurrent corneal erosion, subepithelial opacity, and dry eye are discussed.

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Ultrasound Cyclo Plasty in Eyes with Glaucoma

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Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

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Ultrasound Cyclo Plasty in Eyes with Glaucoma
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Ultrasound Cyclo Plasty in Eyes with Glaucoma

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  • Management strategies range from conservative (corticosteroids) to surgical interventions (flap lift, irrigation, removal).
  • Conclusions:

    • Wound healing post-LASIK can compromise ocular surface homeostasis.
    • Various complications can arise, necessitating specific diagnostic and therapeutic approaches for optimal outcomes.