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Updated: Jun 30, 2026
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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Cerebral cavernous malformations associated with venous anomalies: surgical considerations
Gabriele Wurm1, Mathilde Schnizer, Franz A Fellner
1Department of Neurosurgery, Landes-Nervenklinik Wagner-Jauregg, Linz, Austria. gabriele.wurm@gespag.at
Neurosurgery
|September 25, 2008
Summary
Mixed vascular malformations, often linked to venous malformations (VMs), may be caused by the VM's draining vein. Treating this vein may prevent new lesions and offer a cure for these complex cerebrovascular conditions.
Area of Science:
- Neurology
- Vascular Surgery
- Pathology
Background:
- Mixed cerebrovascular malformations, previously considered rare, are increasingly identified.
- These complex lesions raise questions about shared origins and treatment approaches.
Purpose of the Study:
- To investigate the role of venous malformations (VMs) in the development of mixed cerebrovascular malformations.
- To evaluate the efficacy of treating the VM's draining vein in preventing recurrent or new lesions.
Main Methods:
- A series of 58 patients with cavernous malformations was reviewed, identifying 15 with associated VMs.
- The management of the VM's draining vein in these patients was analyzed, focusing on interventions and outcomes.
Main Results:
- Patients with untreated VM draining veins developed recurrent or de novo lesions.
- Coagulation of the VM draining vein in subsequent patients prevented the development of new malformations.
- Histopathological analysis of new lesions revealed diverse types, including arteriovenous angiomas and capillary telangiectasias.
Conclusions:
- The draining vein of a venous malformation (VM) is hypothesized to be the primary abnormality in mixed vascular malformations.
- Intervention targeting the VM's draining vein may be crucial for the permanent cure of associated malformations.
- Surgical treatment of the VM draining vein shows promise in preventing lesion recurrence and development.
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