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Related Experiment Video

Updated: Jun 30, 2026

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

Published on: July 3, 2020

[Hypophosphatemic osteomalacia].

Catharina Bullmann¹, Georg Benker, Ulrich Rosien

¹Endokrinologikum, Zentrum für Hormon- und Stoffwechselstörungen, Reproduktionsmedizin und Pränatale Medizin, Lornsenstrasse 4-6, Hamburg, Germany. catharina.bullmann@endokrinologikum.com

Medizinische Klinik (Munich, Germany : 1983)

|September 25, 2008

Summary

This summary is machine-generated.

Adult-onset hypophosphatemic osteomalacia, a rare disorder, involves low phosphate and bone softening. Tumor removal led to complete healing in a presented oncogenic osteomalacia case.

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Last Updated: Jun 30, 2026

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

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Published on: July 3, 2020

Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis

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Published on: June 24, 2018

Area of Science:

Endocrinology
Oncology
Bone Metabolism

Background:

Hypophosphatemic osteomalacia is a rare condition presenting in adulthood.
Characterized by hypophosphatemia, renal phosphate wasting, elevated alkaline phosphatase, and osteomalacia.

Observation:

Presents a case of oncogenic (tumor-induced) osteomalacia.
Details the typical clinical presentation, differential diagnoses, and diagnostic workup.

Findings:

Complete healing of osteomalacia was achieved after surgical resection of the causative tumor.
Highlights the importance of identifying and removing the tumor in oncogenic osteomalacia.

Implications:

Discusses novel concepts in hereditary and acquired hypophosphatemic osteomalacia.
Enhances understanding of this rare disease and its management strategies.