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Updated: Jun 30, 2026

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
Published on: July 3, 2020
[Hypophosphatemic osteomalacia]
Catharina Bullmann1, Georg Benker, Ulrich Rosien
1Endokrinologikum, Zentrum für Hormon- und Stoffwechselstörungen, Reproduktionsmedizin und Pränatale Medizin, Lornsenstrasse 4-6, Hamburg, Germany. catharina.bullmann@endokrinologikum.com
Abstract:
Hypophosphatemic osteomalacia first presenting in adulthood is a rare disease. It is characterized by decreased serum phosphate, renal phosphate wasting, elevated alkaline phosphatase, and osteomalacia. The authors present a case with typical constellation of an oncogenic (tumor-induced) osteomalacia, the possible differential diagnosis, diagnostic evaluation, and complete healing after tumor resection. The new concepts of hereditary and acquired hypophosphatemic osteomalacia are discussed helping us understand this rare disease.
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